The Nasal-labial folds ( nasolabial folds ) are often referred to as smile and laugh lines. These facial folds extend from the base of the nostrils to the corners of the mouth. The folds deepen as the cheek volume is lost through aging or weight loss. The most effective treatment is with dermal fillers.

With age or weight loss, the nasal-labial folds begin as creases, then slowly deepen and droop. This also impacts the appearance of the cheek and lower face.

Treating the nasolabial is most effective with dermal fillers.